Found 8 matching trials
Absorption, Metabolism and Excretion of 14C-olorofim in Man PHASE1 Single-centre, open-label, non-randomised, single dose study in 2 cohorts o...
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PRA Health Sciences
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A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Hepatic Impairment PHASE1 A single oral dose study to investigate the PK and safety of olorofim in mi...
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Orange County Research Centre
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Evaluate F901318 (Olorofim) Treatment of Invasive Fungal Infections in Participants Lacking Treatment Options PHASE2 A study to evaluate olorofim (F901318) for the treatment of invasive fungal...
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Valley Fever Institute at Kern Medical Center
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Single Ascending Oral Dose Study of F901318 PHASE1 Double blind, placebo controlled, ascending single oral dose, sequential gr...
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A Phase II Randomized Study to Evaluate Measures for Endpoint Derivation in Patients With Progressive or Refractory Disseminated Coccidioidomycosis (DCM ) Treated With Olorofim Plus Baseline SOC or Placebo Plus Baseline SOC PHASE2 The purpose of this study is to test measurement tools (questionnaire about...
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Multiple Locations
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Drug-drug Interaction (DDI) Study to Assess Effect of Itraconazole and Rifampicin Upon Olorofim PHASE1 This is a Phase 1, single-centre, fixed-sequence, open label, drug-drug int...
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Hammersmith Medicines Research
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A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Renal Impairment PHASE1 A single oral dose study to investigate the PK and safety of olorofim in su...
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Multiple Ascending Oral Dose Study of F901318 in Healthy Subjects PHASE1 Double blind, placebo controlled, ascending multiple (10) oral dose, sequen...
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Simbec Research Ltd
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